Invisibility works great in PvE, but that's because the enemies are programed to ignore you. In the few instances where I can view my character in third person i'm not really all that invisible. Even when standing completely motionless you're still quite blue. I've tried using it in the Crucible and i'm being spotted almost instantly regardless.
Is there any practical use to trying to use invisibility against real flesh and blood players with eyeballs or should it just be ignored in favor of other skills when in PvP?
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It helps you avoid a headshot in a gunfight. Something I like to do is to immediately crouch as soon as I shoot because most people aim above the torso trying to sort of guesstimate where the head is.