The strategy we used was pretty standard for strike bosses. I've found spreading out helps on tougher fights, so we had one guy standing at the door where you enter on the second level, focusing on the boss initially while the two of us left mowed down the adds working towards the back where the gold chest was (a tomb ship appeared as we made it there). After that, we spilt up, each taking a side where those giant grey/silver curved walls were and just passed aggro back and forth between all three of us. As soon as you pull, he fires his mouth laser thing at you, duck behind the wall. When the next wave of adds spawn, the two guys on the ground clean them up before they hit your "tank" on the second floor and go back to spinning the boss around. This strat kept him essentially planted in the middle of the room, making his line of sight easily predictable and the add spawns much more manageable
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Oh and use your primary/secondary to mop up adds, pick up the heavy ammo they drop, use the heavy weapon on the weak spot. If you time it right, you basically have an endless supply of all three ammo types from the waves.