I've never found myself at a disadvantage in crucible for using a hand cannon (the hand cannon is a three-shot kill most of the time), and in my experience of PVE, the hand cannon trumps all other weapons, since it locks enemies in a little stun animation where they recoil in pain when you shoot them. The only absolute downside to hand cannons are their ridiculously long reload speed. Everything else is fine. Anyone care to fill me in why they think hand cannons suck? Using them is so fun! I hope Bungie doesn't listen to the whiners that want Hand Cannons to be secondaries, it's too much fun to use a magnum halo 1 style!
(Edit; this post was made during the beta, before the Exotics and Legendaries had been used, so it is naturally outdated. Keep posting your awesome hand cannons below anyway!)
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Anyone have the red hand ix? I have not seen anyone with one, and if you do have one your thoughts?