Ok, so this is just a theory, it is not confirmed, if you didn't read the title ^-^
What if Osiris became a Vex, and is the final boss of the Glass Vault? And I have one piece of evidence to support this. (Minor Spoilers Ahead) http://destinynews.net/raid-armor-weapons-2/ If you scroll to the warlock armor descriptions, it says this:
Warlock: The helm’s nerve interface incorporates Vex cells. They’re dead, of course. But not too dead to dream. “Slept in the armor last night. Woke to feel my heart stuttering to the pattern of an unknown signal.” “Capable gauntlets. Extremely effective. I have only one piece of advice: never touch a living Vex.” Rumor has it that the exile Osiris came too close to understanding the Vex.
What does the final line mean? "Rumor has it that the exile Osiris came too close to understanding the Vex." Is it possible that Guardians can be corrupted by the Vex?