[url=http://www.independent.co.uk/news/science/revealed-scientists-edit-dna-to-correct-adult-genes-and-cure-diseases-9273555.html][quote]A genetic disease has been cured in living, adult animals for the first time using a revolutionary genome-editing technique that can make the smallest changes to the vast database of the DNA molecule with pinpoint accuracy.
Scientists have used the genome-editing technology to cure adult laboratory mice of an inherited liver disease by correcting a single “letter” of the genetic alphabet which had been mutated in a vital gene involved in liver metabolism.
A similar mutation in the same gene causes the equivalent inherited liver disease in humans – and the successful repair of the genetic defect in laboratory mice raises hopes that the first clinical trials on patients could begin within a few years, scientists said.
The success is the latest achievement in the field of genome editing. This has been transformed by the discovery of Crispr, a technology that allows scientists to make almost any DNA changes at precisely defined points on the chromosomes of animals or plants. Crispr – pronounced “crisper” – was initially discovered in 1987 as an immune defence used by bacteria against invading viruses. Its powerful genome-editing potential in higher animals, including humans, was only fully realised in 2012 and 2013 when scientists showed that it can be combined with a DNA-sniping enzyme called Cas9 and used to edit the human genome.
Since then there has been an explosion of interest in the technology because it is such a simple method of changing the individual letters of the human genome – the 3 billion “base pairs” of the DNA molecule – with an accuracy equivalent to correcting a single misspelt word in a 23-volume encyclopaedia.
In the latest study, scientists at the Massachusetts Institute of Technology (MIT) used Crispr to locate and correct the single mutated DNA base pair in a liver gene known as FAH, which can lead to a fatal build-up of the amino acid tyrosine in humans and has to be treated with drugs and a special diet.
The researchers effectively cured mice suffering from the disease by altering the genetic make-up of about a third of their liver cells using the Crispr technique, which was delivered by high-pressure intravenous injections.[/quote][/url]
I for one did not expect this technology so soon!
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Edited by PandaJerk007: 4/23/2014 5:26:33 AMNow we just need to alter the psychology and biology of humans so that anyone who intentionally kills or severely hurts another human will suffer "death feedback" and die automatically. We'll create a new servant class of humans that are genetically altered just barely enough that the death feedback won't work and we can kill them and they can kill us. Except every normal class citizen will have a gun, and the servant class citizens will live in fear and have nothing. They will just serve our every whim so that they aren't made extinct. And since all the normal humans can't hurt or kill each other, a utopia and new age of peace will be born. [spoiler]Does anyone get the reference? (It's from an anime)[/spoiler]
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Stop, I can only get so erect.
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I can already [i]feel[/i] all the ethical issues this will cause.
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[b][i]They would have to make identical changes to a significant portion of a person's cells to achieve any intended results. [/i][/b]
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Inb4IAmLegend
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http://en.wikipedia.org/wiki/Abolitionism_%28bioethics%29
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Can I become a superhero now?
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I saw this in the paper this morning and thought 'I should share this' <.< I forgot and you beat me too it fair and square. This is so damn cool that it makes me want to go and shoot someone :D
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Time to enlarge my penis!
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>earth lmao that's the best you can do
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Cool.
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