My vote goes toward Intrusion 2's Final Boss, M.A.C.E.
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Edited by Kalameet: 9/9/2013 1:46:24 PMWell, I was playing Borderlands 2 co-op as a Psycho. I join a random lobby and I wind up in a team consisting of 2 sirens, 1 gunzerker, and a psycho(me). The host travels to Terramorphous Peak, and we begin fighting. And it was AWESOME!! Like for the first time I truly experienced a glorious raid fight. No one was using any cheap exploits like Beehawking or DPHU+Grognozzle. Our teamwork was perfect. The sirens were rezzing the shit out of everyone and healing them, too. The Gunzerker was laying down the punishment on Terramorphous, while I was tanking the shit out of him while also doing some large damage. It took about 15 minutes but DAMN did I feel accomplished when he went down. First time I ever killed him on a team without abusing Pride Rock. Best boss experience I've had in a long time.